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In addition, proteins related to neurodevelopment, such as Nr-CAM, NTRK2, and DNER, also showed significant differences

[Google Scholar] Reeves R

The data show that, despite Avapro being a hugely successful drug for Sanofi, having generated peak sales in excess of $1.2 billion as recently as 2010, 150 mg of the drug did not achieve the primary endpoint in reducing incidence of DN in risk patients

titration helps identify the minimum effective dose for individual response [2]
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